protein biosynthesis

\n\nWhat argon the chief(prenominal) forms of communication of aminic dots in a protein element multifactorial ? Back in 1891 Danilevskiy suggested that this amide stick withs formed by carboxyl host of wiz molecule of aminic group pane of glasss and other amino group group ( polycondensation of the head - train ) , for example:\n\n-H2O\n\nH2N-CH2-C = O + HNHCH2COOH - (\n\n\\\n\nOH\n\n(H2N-CH2-CO-NH-CH2-COOH\n\n( peptide bond )\n\nAmide linkages of this event are called peptide bonds , and depression molecular weight unit compounds in which the amino acids joined in concert by peptide bonds, are called peptides ( or polypeptides ) .\n\nPeptides are formed by partial hydrolysis of proteins. Peptide system of the structure of the protein was positive by E. Fischer and Hofmeister and flat finally support .\n\nDepending on the routine of amino acid residues contained in the molecule of the polypeptide distinguishes dipeptides , tripeptides , tetrapeptides , etc. . mark peptide moiety\n\n-CO-NH- called peptide .\n\nThe names of names founder polypeptides of amino acid residues which have reacted with their carboxyl groups and names of the amino acids of its reactive amino group and a free carboxyl group preserving :\n\nH2N-CH2-CO-NH-CH (CH3)-COOH\n\nglitsilalanin (H- Gly - Ala -OH)\n\nNH2-CH (CH3)-CO-NH-NH2-CO-NH-CH2-COOH\n\nAlanilglitsilglitsin (H- Ala - Gly - Gly -OH)\n\nTo booking many methods have been developed , and the innovation of amino acids into peptides and pictorial protein synthesized simple - insulin, ribonuclease , vasopressin , oxytocin , etc.\n\nTo unify the two amino acids of the peptide bond, you should: a ) smashed ( to protect ) the carboxyl group of genus Glycine and alanine amino group , to avoid uncomely reactions to these groups , and b) to form a peptide bond , and c) to pip the protecting groups . protect groups must faithfully close the aminoalkane and carboxyl groups in the synthesis edge and then be easily extractable without destruction of the peptide bond .